Cover Feature: Bioinspired Transformations Using Strictosidine Aglycones: Divergent Total Syntheses of Monoterpenoid Indole Alkaloids in the Early Stage of Biosynthesis (Chem. Eur. J. 10/2022)
نویسندگان
چکیده
Strictosidine is an important molecule in the biosynthesis of higher plants that gives rise to a great variety structures. A series bioinspired transformations are applied convert strictosidine aglycones into monoterpenoid indole alkaloids reported. In this image, aglycon depicted as gavel produces treasure Japanese folktales represent production various natural products from single molecule. The produced study will be very useful library for drug discovery. More information can found Research Article by J. Sakamoto and H. Ishikawa (DOI: 10.1002/chem.202104052).
منابع مشابه
The Biosynthesis of Monoterpenoid lndole Alkaloids from Strictosidine
The differential incorporation of doubly labelled strictosidine and vincoside into several indole alkaloids belonging to the Corynanthe (3a and 3p series), Aspidosperma, and lboga types in three plant families has been studied, and it has been demonstrated that only strictosidine is incorporated while vincoside is metabolically inert in these plants with regard to alkaloid formation. During the...
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ژورنال
عنوان ژورنال: Chemistry: A European Journal
سال: 2022
ISSN: ['0947-6539', '1521-3765']
DOI: https://doi.org/10.1002/chem.202200315